IRG1 and Inducible Nitric Oxide Synthase Act Redundantly with Other Interferon-Gamma-Induced Factors To Restrict Intracellular Replication of Legionella pneumophila

Interferon gamma (IFN-γ) restricts the intracellular replication of many pathogens, but the mechanism by which IFN-γ confers cell-intrinsic pathogen resistance remains unclear. For example, intracellular replication of the bacterial pathogen Legionella pneumophila in macrophages is potently curtaile...

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發表在:mBio
Main Authors: Price, Jordan V., Russo, Daniel, Ji, Daisy X., Chavez, Roberto A., DiPeso, Lucian, Lee, Angus Yiu-Fai, Coers, Jörn, Vance, Russell E.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2019
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851286/
https://ncbi.nlm.nih.gov/pubmed/31719183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02629-19
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