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Activation of RNase L in Egyptian Rousette Bat-Derived RoNi/7 Cells Is Dependent Primarily on OAS3 and Independent of MAVS Signaling

Bats are reservoirs for many RNA viruses that are highly pathogenic in humans yet relatively apathogenic in the natural host. It has been suggested that differences in innate immunity are responsible. The antiviral OAS-RNase L pathway is well characterized in humans, but there is little known about...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Li, Yize, Dong, Beihua, Wei, Zuzhang, Silverman, Robert H., Weiss, Susan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851283/
https://ncbi.nlm.nih.gov/pubmed/31719180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02414-19
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