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Unpredictable Nanoparticle Retention in Commonly Used Plastic Syringes Introduces Dosage Uncertainties That May Compromise the Accuracy of Nanomedicine and Nanotoxicology Studies

In recent animal experiments with suspensions of radiolabeled TiO(2) nanoparticles large and highly variable radioactivity fractions were retained in disposable plastic syringes. After unloading between 10% and up to 70% of the loaded dose were still present in the syringes. As a consequence the eff...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Holzwarth, Uwe, Cossío, Unai, Llop, Jordi, Kreyling, Wolfgang G.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851237/
https://ncbi.nlm.nih.gov/pubmed/31780932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01293
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