Use of an alternative method to evaluate erythema severity in a clinical trial: difference in vehicle response with evaluation of baseline and postdose photographs for effect of oxymetazoline cream 1·0% for persistent erythema of rosacea in a phase IV study

BACKGROUND: Once‐daily topical oxymetazoline cream 1·0% significantly reduced persistent facial erythema of rosacea in trials requiring live, static patient assessments. OBJECTIVES: To evaluate critically the methodology of clinical trials that require live, static patient assessments by determining...

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Vydáno v:Br J Dermatol
Hlavní autoři: Eichenfield, L.F., Del Rosso, J.Q., Tan, J.K.L., Hebert, A.A., Webster, G.F., Harper, J., Baldwin, H.E., Kircik, L.H., Stein‐Gold, L., Kaoukhov, A., Alvandi, N.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850476/
https://ncbi.nlm.nih.gov/pubmed/30500065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjd.17462
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