Detachment of the RNA degradosome from the inner membrane of Escherichia coli results in a global slowdown of mRNA degradation, proteolysis of RNase E and increased turnover of ribosome‐free transcripts

The reason for RNase E attachment to the inner membrane is largely unknown. To understand the cell biology of RNA degradation, we have characterized a strain expressing RNase E lacking the membrane attachment site (cytoplasmic RNase E). Genome‐wide data show a global slowdown in mRNA degradation. Th...

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Vydáno v:Mol Microbiol
Hlavní autoři: Hadjeras, Lydia, Poljak, Leonora, Bouvier, Marie, Morin‐Ogier, Quentin, Canal, Isabelle, Cocaign‐Bousquet, Muriel, Girbal, Laurence, Carpousis, Agamemnon J.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850036/
https://ncbi.nlm.nih.gov/pubmed/30903628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.14248
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