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Clinical Practice Guidance: Surveillance for phaeochromocytoma and paraganglioma in paediatric succinate dehydrogenase gene mutation carriers

The succinate dehydrogenase (SDH) enzyme complex functions as a key enzyme coupling the oxidation of succinate to fumarate in the citric acid cycle. Inactivation of this enzyme complex results in the cellular accumulation of the oncometabolite succinate, which is postulated to be a key driver in tum...

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Détails bibliographiques
Publié dans:Clin Endocrinol (Oxf)
Auteurs principaux: Wong, Mei Yin, Andrews, Katrina A., Challis, Benjamin G., Park, Soo‐Mi, Acerini, Carlo L., Maher, Eamonn R., Casey, Ruth T.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850004/
https://ncbi.nlm.nih.gov/pubmed/30589099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cen.13926
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