Mucosal IL13RA2 expression predicts nonresponse to anti‐TNF therapy in Crohn's disease

BACKGROUND: Ileocolonic expression of IL13RA2 has been identified as a predictive marker for nonresponsiveness to infliximab (IFX) in patients with Crohn's disease (CD). AIM: To validate the IL13RA2 biomarker, study its anti‐TNF specificity and get a better understanding of the underlying biolo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Aliment Pharmacol Ther
Prif Awduron: Verstockt, Bram, Verstockt, Sare, Creyns, Brecht, Tops, Sophie, Van Assche, Gert, Gils, Ann, Ceuppens, Jan L., Vermeire, Séverine, Ferrante, Marc, Breynaert, Christine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Mucosal Il13ra2 Expression and Response to Anti‐tnf in Crohn's Disease
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849553/
https://ncbi.nlm.nih.gov/pubmed/30663072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apt.15126
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