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Advances and perspectives of PARP inhibitors
DNA damage repair deficiency leads to the increased risk of genome instability and oncogenic transformation. In the meanwhile, this deficiency could be exploited for cancer treatment by inducing excessive genome instability and catastrophic DNA damage. Continuous DNA replication in cancer cells lead...
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| Publicado no: | Exp Hematol Oncol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6849303/ https://ncbi.nlm.nih.gov/pubmed/31737426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-019-0154-9 |
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