Tim-3 signaling blockade with α-lactose induces compensatory TIGIT expression in Plasmodium berghei ANKA-infected mice

BACKGROUND: Malaria, one of the largest health burdens worldwide, is caused by Plasmodium spp. infection. Upon infection, the host’s immune system begins to clear the parasites. However, Plasmodium species have evolved to escape the host’s immune clearance. T-cell immunoglobulin and mucin domain 3 (...

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Detalhes bibliográficos
Publicado no:Parasit Vectors
Main Authors: Zhang, Yiwei, Jiang, Ning, Zhang, Ting, Chen, Ran, Feng, Ying, Sang, Xiaoyu, Yang, Na, Chen, Qijun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849286/
https://ncbi.nlm.nih.gov/pubmed/31711531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-019-3788-x
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