An integrative methodology based on protein-protein interaction networks for identification and functional annotation of disease-relevant genes applied to channelopathies

BACKGROUND: Biologically data-driven networks have become powerful analytical tools that handle massive, heterogeneous datasets generated from biomedical fields. Protein-protein interaction networks can identify the most relevant structures directly tied to biological functions. Functional enrichmen...

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Detalles Bibliográficos
Publicado en:BMC Bioinformatics
Autores principales: Marín, Milagros, Esteban, Francisco J., Ramírez-Rodrigo, Hilario, Ros, Eduardo, Sáez-Lara, María José
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
Materias:
Methodology Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849233/
https://ncbi.nlm.nih.gov/pubmed/31718537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3162-1
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