Mitochondrial oxidative stress-induced transcript variants of ATF3 mediate lipotoxic brain microvascular injury

Elevation of blood triglycerides, primarily triglyceride-rich lipoproteins (TGRL), is an independent risk factor for cardiovascular disease and vascular dementia (VaD). Accumulating evidence indicates that both atherosclerosis and VaD are linked to vascular inflammation. However, the role of TGRL in...

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Pubblicato in:Free Radic Biol Med
Autori principali: Nyunt, Tun, Britton, Monica, Wanichthanarak, Kwanjeera, Budamagunta, Madhu, Voss, John C., Wilson, Dennis W., Rutledge, John C., Aung, Hnin H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6848793/
https://ncbi.nlm.nih.gov/pubmed/31356870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2019.07.024
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