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Cytochrome P450 2E1-deficient MRL+/+ mice are less susceptible to trichloroethene-mediated autoimmunity: Involvement of oxidative stress-responsive signaling pathways
Reactive trichloroethene (TCE) metabolites and oxidative stress are involved in TCE-mediated autoimmunity, as evident from our earlier studies in MRL+/+ mice. However, molecular mechanisms underlying TCE-mediated autoimmunity remain largely unknown. Cytochrome P450 2E1 (CYP2E1), the major enzyme res...
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| Publicado no: | Free Radic Biol Med |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6848790/ https://ncbi.nlm.nih.gov/pubmed/31446053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2019.08.022 |
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