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Oncogenes, tumor suppressor and differentiation genes represent the oldest human gene classes and evolve concurrently

Earlier we showed that human genome contains many evolutionarily young or novel genes with tumor-specific or tumor-predominant expression. We suggest calling such genes Tumor Specifically Expressed, Evolutionarily New (TSEEN) genes. In this paper we performed a study of the evolutionary ages of diff...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Makashov, A. A., Malov, S. V., Kozlov, A. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6848199/
https://ncbi.nlm.nih.gov/pubmed/31712655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52835-w
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