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KRAS regulation by small non-coding RNAs and SNARE proteins

KRAS receives and relays signals at the plasma membrane (PM) where it transmits extracellular growth factor signals to downstream effectors. SNORD50A/B were recently found to bind KRAS and inhibit its tumorigenic action by unknown mechanisms. KRAS proximity protein labeling was therefore undertaken...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Che, Yonglu, Siprashvili, Zurab, Kovalski, Joanna R., Jiang, Tiffany, Wozniak, Glenn, Elcavage, Lara, Khavari, Paul A.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6848142/
https://ncbi.nlm.nih.gov/pubmed/31712554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13106-4
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