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A gene regulatory network to control EMT programs in development and disease

The Epithelial to Mesenchymal Transition (EMT) regulates cell plasticity during embryonic development and in disease. It is dynamically orchestrated by transcription factors (EMT-TFs), including Snail, Zeb, Twist and Prrx, all activated by TGF-β among other signals. Here we find that Snail1 and Prrx...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Fazilaty, Hassan, Rago, Luciano, Kass Youssef, Khalil, Ocaña, Oscar H., Garcia-Asencio, Francisco, Arcas, Aida, Galceran, Juan, Nieto, M. Angela
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6848104/
https://ncbi.nlm.nih.gov/pubmed/31712603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13091-8
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