In Situ Forming Injectable Hydrogel For Encapsulation Of Nanoiguratimod And Sustained Release Of Therapeutics

BACKGROUND: Iguratimod (IGUR) is a novel disease-modifying antirheumatic drug used for treating rheumatoid arthritis (RA). To improve its bioavailability and to alleviate gastrointestinal side effects, we changed the formulation into nanoiguratimod-loaded hydrogel (NanoIGUR-loaded hydrogel) composit...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Ma, Zhenzhen, Tao, Cheng, Sun, Lin, Qi, Shengbei, Le, Yuan, Wang, Jiexin, Li, Changhong, Liu, Xiangyuan, Zhang, Jianjun, Zhao, Jinxia
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847989/
https://ncbi.nlm.nih.gov/pubmed/31806967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S214507
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