CMET-18. IMPACT OF KRAS MUTATION STATUS ON THE EFFICACY OF IMMUNOTHERAPY IN LUNG CANCER BRAIN METASTASES

BACKGROUND: Immunotherapy is increasingly used in patients with non-small cell lung cancer brain metastases (NSCLCBM). KRAS mutations are associated with worse prognosis and there is no FDA approved targeted therapy. KRAS mutations are associated with increased expression of PD-L1. We evaluated the...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Lauko, Adam, Ali, Assad, Sagar, Soumya, Barnett, Addison, Li, Hong, Chao, Samuel, Stevens, Glen, Pennell, Nathan, Peereboom, David, Yu, Jennifer, Murphy, Erin, Angelov, Lilyana, Funchain, Pauline, Mohammadi, Alireza, Suh, John, Barnett, Gene, Ahluwalia, Manmeet
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
CNS Metastasis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847893/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.219
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