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PDTM-30. UNDERSTANDING THE EFFECTS OF MOLECULAR SIZE ON VOLUME OF DISTRIBUTION IN CONVECTION-ENHANCED DELIVERY

BACKGROUND: Diffuse midline gliomas harboring the H3K27M mutation, previously known as diffuse intrinsic pontine gliomas (DIPG), are rare and aggressive pediatric brain tumors. Over 100 clinical trials with different chemotherapeutics have failed to show any therapeutic benefit. One reason for failu...

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Bibliografiset tiedot
Julkaisussa:Neuro Oncol
Päätekijät: Power, Erica, Rechberger, Julian, Zhang, Liang, Daniels, David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847886/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.806
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