EPID-19. SHARED GENOMIC ARCHITECTURE OF GLIOMA AND NEURO-COGNITIVE AND NEURO-PSYCHIATRIC TRAITS REVEALED BY LD-SCORE REGRESSION

BACKGROUND: Genome-wide analyses estimate glioma heritability at 25%, yet known risk loci account for just one-third of this risk and suggest that sporadic glioma is a highly polygenic disease with hitherto unaccounted for genomic architecture. LD-score regression leverages results from genome-wide...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Walsh, Kyle, Ostrom, Quinn, Zhang, Chenan, Edelson, Jacob, Shen, Erica, Byun, Jinyoung, Han, Younghun, Amos, Christopher, Bondy, Melissa
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Epidemiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847871/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.319
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