CBMT-27. ABERRANT AMINO ACID METABOLISM EXPOSE NOVEL FUNCTIONAL VULNERABILITIES IN GLIOBLASTOMA

Despite advances in molecularly characterizing glioblastoma, metabolic alterations driving its aggressive phenotype are only beginning to be recognized. Integrative cross-platform analyses coupling global metabolomic and gene expression profiling identified aberrant amino acid (AA) metabolism as a c...

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Udgivet i:Neuro Oncol
Main Authors: Prabhu, Antony, Guastella, Anthony, Kant, Shiva, Kesarwani, Pravin, Nakano, Ichiro, Chinnaiyan, Prakash
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Cell Biology and Metabolism
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847795/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.149
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