EXTH-48. GALECTIN-1 INHIBITION SENSITIZES RADIATION TREATMENT IN A PRE-CLINICAL MODEL OF GLIOBLASTOMA

Radioresistance remains a major clinical challenge in glioblastoma (GB) therapy. However, the mechanism for the development of radioresistance in GB is unclear. Mounting evidence suggests that Galectin-1 (Gal1: a carbohydrate-binding protein galectin-1) contributes to the radioresistance of GB tumor...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Henderson, Fraser, Das, Arabinda, Kanginakudru, Indira, McDonald, Daniel G, Kosnik Infinger, Libby, Vandergrift III, William, Varma, Abhay, Vanek, Kenneth N, Lindhorst, Scott, Patel, Sunil, Cachia, David
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
Assuntos:
Experimental Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847700/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.380
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