EXTH-38. ENGINEERED EXOSOMES FOR THERAPEUTIC GENE DELIVERY IN BRAIN TUMORS

The poor outcome of patients with glioblastoma (GBM) is at least partly due to the inability to deliver therapeutic agents to the tumor. We have shown that exosomes, naturally occurring nano-size extracellular vesicles, are capable of delivering antiglioma microRNAs (MiRs) to brain tumors (Lang, FM...

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: McDonald, Malcolm, Hasan, Irtiza, Adachi, Satoshi, Gumin, Joy, Ledbetter, Daniel, Daou, Marc, Gopakumar, Sricharan, Momin, Eric, Long, Lihong, Phillips, Lynette, Parker-Kerrigan, Brittany, Hossain, Anwar, Lang, Frederick
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847646/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.370
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