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STEM-19. RESISTANCE IS FUTILE: UNDERSTANDING AND TARGETING THE CDK5-CREB1-MCL1 AXIS TO PREVENT RADIATION RESISTANCE IN GLIOMA STEM CELLS
Glioblastoma is a WHO Grade IV malignant brain tumor with a 95% mortality rate within 2–5 years of diagnosis. This prognosis has not improved in the last 30 years, and with standardized radiation therapy, the cancer always recurs. It is not yet clear why the disease relapses, however recent studies...
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| Publicat a: | Neuro Oncol |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6847569/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.992 |
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