CMET-30. COMPREHENSIVE METHYLOME ANALYSIS OF EGFR-MUTANT PRIMARY LUNG ADENOCARCINOMA AND MATCHED BRAIN METASTASIS

Brain metastasis (BM) in patients with EGFR-mutant lung adenocarcinoma is a major determinant of overall survival. Novel insight into the genetic and epigenetic underpinnings of BM development is lacking. The aim of this study is to compare the methylome of EGFR-mutant primary lung adenocarcinoma (E...

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Publicat a:Neuro Oncol
Autors principals: Mamatjan, Yasin, Cabanero, Michael, Zuccato, Jeffrey, Weiss, Jessica, Karimi, Shirin, Sorotsky, Hadas, Tsao, Ming, Aldape, Kenneth, Shepherd, Frances, Zadeh, Gelareh
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
CNS Metastasis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847451/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.231
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