PATH-27. GIANT CELL GLIOBLASTOMA DOES NOT REPRESENT A DISTINCT TUMOUR ENTITY BUT STRATIFIES INTO DIFFERENT GENETICALLY DEFINED SUBTYPES

BACKGROUND: Giant cell glioblastoma (G-GBM) is a rare variant of glioblastoma (GBM) characterized by large often multinucleated tumour cells. G-GBM occurs most frequently de novo; in contrast to IDH wildtype GBM they carry TP53 mutations in high frequency. METHODS: We collected 58 G-GBM from 25 chil...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Wiedey, Anna, Dörner, Evelyn, zur Mühlen, Anja, de Azevedo Pinto, Maria, Kramm, Christof, Waha, Andreas, Pietsch, Torsten
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
Assuntos:
Molecular Pathology and Classification - Adult and Pediatric
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847427/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.623
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