DDIS-26. HIGH-THROUGHPUT DRUG SCREENING OF MENINGIOMAS IDENTIFIES HDAC INHIBITORS AS PROMISING TARGETS ACROSS GRADES

Meningiomas are a common central nervous system (CNS) tumor, accounting for one third of CNS neoplasms. To date, no FDA approved pharmacotherapy exists for meningiomas. In an effort to identify potential treatments for meningiomas we created a culture system that allows us to grow and screen tumors...

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Publicat a:Neuro Oncol
Autors principals: Tatman, Philip, Fringuello, Anthony, Wroblewski, Teddy, Scherer, Sam, Foreman, William, Ryan Ormond, D, Damek, Denise, Lillehei, Kevin, Jensen, Randy, Graner, Michael
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Drug Discovery
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847367/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.277
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