PATH-45. DIFFERENT TYPES OF HYPERMUTATOR PHENOTYPE OF GLIOBLASTOMA ACCORDING TO MUTATION PATTERNS OF MISMATCH REPAIR GENES

BACKGROUND: Although precision medicine has been widely applied to routine care, only few molecular targeted drugs have been developed for glioma. Immune checkpoint inhibitors hold a potential promise to improve outcome of malignant glioma especially with the hypermutator phenotype. Mismatch repair...

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Publicado en:Neuro Oncol
Autores principales: Saito, Kuniaki, Shimizu, Saki, Nozaki, Eriko, Kobayashi, Keiichi, Sasaki, Nobuyoshi, Yamagishi, Yuki, Shiokawa, Yoshiaki, Nagane, Motoo
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
Materias:
Molecular Pathology and Classification - Adult and Pediatric
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847252/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.641
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