TMOD-31. ADAPTING ENGINEERED CELL THERAPIES TO UNDERSTAND AND OVERCOME GLIOBLASTOMA RESISTANCE USING INTEGRATED IN VIVO AND EX VIVO MODELS

Genetically engineered neural stem cells (NSCs) are a promising therapy for the highly aggressive brain cancer glioblastoma (GBM), yet treatment durability remains a major challenge. We sought to define the events that contribute to dynamic adaption of GBM during NSC treatment and develop strategies...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Satterlee, Andrew, Dunn, Denise, Floyd, Scott, Hingtgen, Shawn
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Tumor Models
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847248/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1130
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