ACTR-18. A PHASE IB/II CLINICAL TRIAL OF DODECAFLUOROPENTANE EMULSION (DDFPE) AS A RADIOSENSITIZER IN GLIOBLASTOMA

BACKGROUND: Tumor hypoxia decreases the response of glioblastoma multiforme (GBM) to radiotherapy (RT) and chemotherapy (temozolomide[TMZ]). The purpose of this study was to evaluate the safety and efficacy of a novel oxygen therapeutic, dodecafluoropentane emulsion (DDFPe), in chemoradiation treatm...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Lickliter, Jason, Ruben, Jeremy, Jennens, Ross, Kichenadasse, Ganessan, Gzell, Cecelia, Mason, Ralph, Carmody, Raymond, Becker, Jennifer, Stea, Baldassarre, Zhou, Heling, Sellenger, Michael, Longacre, Olivia, Graham, Kaitlin, Unger, Evan
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Adult Clinical Trials - Non-Immunologic
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847233/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.061
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