PDCT-05. FINAL RESULTS OF THE VINILO OPEN-LABEL PHASE II RANDOMIZED TRIAL FOR PEDIATRIC LOW-GRADE GLIOMAS (pLGG) COMPARING THE COMBINATION VINBLASTINE-NILOTINIB WITH VINBLASTINE ALONE

Chemotherapy is the mainstay of non-surgical treatment in pLGG but many patients progress again after the end of the first treatment. Apart from the standard carboplatin-vincristine, new regimens with less toxicity are therefore desirable. Single agent vinblastine is an established regimen. PDGFRA T...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Grill, Jacques, Brard, Caroline, Picton, Sue, Cruz, Ofelia, Schouten-vanMetteren, A Y N, Marie Sehested, Astrid, Gerber, Nicolas, Entz-Werle, Natacha, Le Deley, Marie-Cécile, Dangouloff-Ros, Volodia, Varlet, Pascale
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Pediatric Clinical Trials
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847172/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.769
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