SCIDOT-48. EVALUATING THE THERAPEUTIC EFFICACY AND CONVECTION ENHANCED DELIVERY (CED) TOXICITY ANALYSIS OF CDK4/6 INHIBITOR PALBOCICLIB FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

DIPG is a devastating, aggressive brain tumor of childhood. No chemotherapeutic agent has so far shown significant clinical efficacy and focal radiation therapy provides only temporary relief. Recent studies on the genomic aberrations of pediatric gliomas have shown that a subset of these tumors har...

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Опубликовано в: :Neuro Oncol
Главные авторы: Lee, Dennis, Maachani, Uday, Adeuyan, Oluwaseyi, Guadix, Sergio, Souweidane, Mark
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2019
Предметы:
Abstracts from the 3rd Sno-Scidot Joint Conference on Therapeutic Delivery to the CNS
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847080/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1184
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