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STEM-11. CD146/MCAM REGULATES MESENCHYMAL PROPERTIES, STEMNESS, RADIO-RESISTANCE AND YAP ACTIVITY IN GLIOBLASTOMA

Glioblastoma (GBM), a highly malignant and lethal brain tumor, is characterized by diffuse invasion into the brain and chemoradiotherapy resistance resulting in recurrences and poor prognosis. In this study we examined if the cell adhesion molecule CD146/ MCAM is contributing to the malignant proper...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Liang, Yuan-Ke, Voshart, Daniëlle, den Dunnen, Wilfred, Barazzuol, Lara, Kruyt, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846968/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.985
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