CBMT-31. HDAC INHIBITION DIMINISHES THE GROWTH OF ENDOGENOUS IDH MUTANT GLIOMAS

Histone deacetylase inhibitors (HDACi’s) have emerged as a promising class of drugs for treatment of malignancies such as glioblastoma (GBM). Several studies have demonstrated the anti-tumor property of HDACi’s against GBM in both in vitro and in vivo experiments. Nonetheless, in clinical trials, HD...

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Publicat a:Neuro Oncol
Autors principals: Elahi, Lubayna, Garrett, Matthew, Guo, Lea, Condro, Michael, Kawaguchi, Riki, Mehta, Shwetal, Lai, Albert, Pope, Whitney, Kornblum, Harley
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Cell Biology and Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846940/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.153
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