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ACTR-56. PHASE II TRIAL OF NILOTINIB IN PDGFR-ALPHA ENRICHED RECURRENT GLIOBLASTOMA

BACKGROUND: This phase II study was designed to determine the efficacy of nilotinib in a biomarker-selected population of recurrent glioblastoma (GBM), enriched for platelet-derived growth factor receptor-alpha (PDGFR-alpha) activation. Nilotinib is a multi-kinase inhibitor approved as treatment for...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Picconi, David, Juarez, Tiffany, Kesari, Santosh
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846918/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.098
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