RDNA-14. RADIATION-INDUCED miR-4516 CONTRIBUTES TO RADIO-RESISTANCE AND PROMOTES AGGRESSIVE PHENOTYPE IN GLIOBLASTOMA

BACKGROUND: Glioblastoma is the most aggressive brain tumor with poor prognosis despite the best available treatment. MicroRNAs (miRNAs) are emerging as promising, novel prognostic biomarkers and therapeutic targets in glioblastoma. In a previous study, we demonstrated that miR-4516 predicts poor pr...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Sebastian, Ebin, Cui, Tiantian, Hlavin Bell, Erica, McElroy, Joseph, Johnson, Benjamin, Manchanda Gulati, Pooja, Geurts, Marjolein, Paixao Becker, Aline, Fleming, Jessica, Jaharul Haque, S, Robe, Pierre, Chakravarti, Arnab
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Radiation Biology and DNA Repair
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846900/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.873
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