DDIS-31. A NOVEL BRAIN-PERMEANT CHEMOTHERAPEUTIC AGENT FOR THE TREATMENT OF BREAST CANCER LEPTOMENINGEAL METASTASIS

Leptomeningeal metastasis (LM), a spread of cancer to the cerebrospinal fluid and meninges, is universally and rapidly fatal due to poor detection and no effective treatment. Breast cancers account for a majority of LMs from solid tumors, with triple-negative breast cancers (TNBCs) having the highes...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Deng, Jiaojiao, Chernikova, Sophia, Fischer, Wolf-Nicolas, Koller, Kerry, Jandeleit, Bernd, Ringold, Gordon, Hayden Gephart, Melanie
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Drug Discovery
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846886/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.282
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