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THE ROLE OF CAPRIN-1 PROTEIN DYSREGULATION IN SYNAPSE DECLINE LEADING TO PROGRESSION OF TAUOPATHIES

Many neurodegenerative diseases are characterized by accumulation of proteins such as tau, a microtubule stabilization protein. Toxic tau forms tangles and affects neuronal synapse function, an early step of neurodegeneration. To focus on synapse function, we highlighted Caprin-1 protein. Through ge...

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Bibliografische gegevens
Gepubliceerd in:Innov Aging
Hoofdauteurs: Fastenau, Caitlyn, Cifuentes, Helen, Kauwe, Grant, Tracy, Tara
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846662/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igz038.3078
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