TMOD-33. AN INTEGRATED APPROACH COMBINING MATHEMATICAL AND GENOMIC METHODS TO REVEAL THE OPTIMAL TIMING OF THERAPEUTIC INTERVENTION IN WHO GRADE II DIFFUSE GLIOMA

BACKGROUND: In WHO grade II diffuse gliomas (low-grade gliomas, hereafter called LGGs), chemotherapy and radiotherapy contribute to prolonged survival but could induce somatic mutations. The optimal timing of treatment in LGGs remain poorly understood. To delineate this, we designed a mathematical m...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Aoki, Kosuke, Yamamoto, Takashi, Suzuki, Hiromichi, Maeda, Sachi, Ranjit, Melissa, Motomura, Kazuya, Nakamura, Hideo, Narita, Yoshitaka, Nakada, Mitsutoshi, Deguchi, Shoichi, Mizoguchi, Masahiro, Momii, Yasutomo, Muragaki, Yoshihiro, Abe, Tatsuya, Akimoto, Jiro, Wakabayashi, Toshihiko, Haeno, Hiroshi, Natsume, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Tumor Models
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846405/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1132
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