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INCREASED C3 IN THE AGING BRAIN PROMOTES INFLAMMATORY TRANSITION IN ENDOTHELIAL CELLS

Innate immunity has been implicated in normal aging, and age-related disease. The connection between age-related neuroinflammation and change in brain vasculature prior to disease onset remains poorly understood. The complement pathway is an established mediator of neuroinflammation, and increased c...

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Dettagli Bibliografici
Pubblicato in:Innov Aging
Autori principali: Propson, Nicholas E, Litvinchuk, Alexandra, Roy, Ethan R, Contreras, Bianca, Cao, Wei, Zheng, Hui
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846236/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igz038.3093
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