TMIC-22. IDENTIFICATION OF CANCER-ASSOCIATED FIBROBLASTS IN GLIOBLASTOMA and Defining Their Protumoral Effects

While cancer-associated fibroblasts (CAFs) and their pro-tumoral effects have been demonstrated in systemic cancers, CAFs had been presumed absent in glioblastoma given the lack of normal fibroblasts in the healthy brain. Here, we show that 5–26% (mean=12%) of cells in human glioblastomas express CA...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Rick, Jonathan, Nguyen, Alan, Chandra, Ankush, Wadhwa, Harsh, Shah, Sumedh, Wang, Lin, Lau, Darryl, Safaee, Michael, Ordaz, Angel, Yagnik, Garima, Diaz, Aaron, Aghi, Manish
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Tumor Microenvironment
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846106/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1056
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