TMIC-02. JUNCTIONAL ADHESION MOLECULE-A (JAM-A) DEFICIENCY DRIVES SEX-SPECIFIC DIFFERENCES IN GLIOBLASTOMA PROGRESSION VIA DIFFERENTIAL MICROGLIA RESPONSES IN THE TUMOR MICROENVIRONMENT

Despite the male preponderance for developing glioblastoma (GBM) and better survival outcomes in females, current treatment paradigms do not account for biological sex as a biological or clinical variable. Sex-specific molecular alterations that drive tumor cell growth and therapy response have been...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Turaga, Soumya, Silver, Daniel, Paouri, Evi, Bayik, Defne, Peng, Sen, Connor, James, Barnholtz-Sloan, Jill, Rubin, Joshua, Berens, Michael, Davalos, Dimitrios, Lathia, Justin
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
Assuntos:
Tumor Microenvironment
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845538/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1036
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