TMIC-02. JUNCTIONAL ADHESION MOLECULE-A (JAM-A) DEFICIENCY DRIVES SEX-SPECIFIC DIFFERENCES IN GLIOBLASTOMA PROGRESSION VIA DIFFERENTIAL MICROGLIA RESPONSES IN THE TUMOR MICROENVIRONMENT

Despite the male preponderance for developing glioblastoma (GBM) and better survival outcomes in females, current treatment paradigms do not account for biological sex as a biological or clinical variable. Sex-specific molecular alterations that drive tumor cell growth and therapy response have been...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Autores principales: Turaga, Soumya, Silver, Daniel, Paouri, Evi, Bayik, Defne, Peng, Sen, Connor, James, Barnholtz-Sloan, Jill, Rubin, Joshua, Berens, Michael, Davalos, Dimitrios, Lathia, Justin
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
Materias:
Tumor Microenvironment
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845538/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1036
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