TMIC-02. JUNCTIONAL ADHESION MOLECULE-A (JAM-A) DEFICIENCY DRIVES SEX-SPECIFIC DIFFERENCES IN GLIOBLASTOMA PROGRESSION VIA DIFFERENTIAL MICROGLIA RESPONSES IN THE TUMOR MICROENVIRONMENT

Despite the male preponderance for developing glioblastoma (GBM) and better survival outcomes in females, current treatment paradigms do not account for biological sex as a biological or clinical variable. Sex-specific molecular alterations that drive tumor cell growth and therapy response have been...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Turaga, Soumya, Silver, Daniel, Paouri, Evi, Bayik, Defne, Peng, Sen, Connor, James, Barnholtz-Sloan, Jill, Rubin, Joshua, Berens, Michael, Davalos, Dimitrios, Lathia, Justin
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Tumor Microenvironment
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845538/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1036
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