TMIC-02. JUNCTIONAL ADHESION MOLECULE-A (JAM-A) DEFICIENCY DRIVES SEX-SPECIFIC DIFFERENCES IN GLIOBLASTOMA PROGRESSION VIA DIFFERENTIAL MICROGLIA RESPONSES IN THE TUMOR MICROENVIRONMENT

Despite the male preponderance for developing glioblastoma (GBM) and better survival outcomes in females, current treatment paradigms do not account for biological sex as a biological or clinical variable. Sex-specific molecular alterations that drive tumor cell growth and therapy response have been...

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Turaga, Soumya, Silver, Daniel, Paouri, Evi, Bayik, Defne, Peng, Sen, Connor, James, Barnholtz-Sloan, Jill, Rubin, Joshua, Berens, Michael, Davalos, Dimitrios, Lathia, Justin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Tumor Microenvironment
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845538/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1036
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