Paracrine signalling of AGR2 stimulates RhoA function in fibroblasts and modulates cell elongation and migration

The most prominent cancer-associated fibroblasts (CAFs) in tumor stroma is known to form a protective structure to support tumor growth. Anterior gradient-2 (AGR2), a tumor secretory protein is believed to play a pivotal role during tumor microenvironment (TME) development. Here, we report that extr...

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Bibliografske podrobnosti
izdano v:Cell Adh Migr
Main Authors: Mangukiya, Hitesh Bhagavanbhai, Negi, Hema, Merugu, Siva Bharath, Sehar, Qudsia, Mashausi, Dhahiri Saidi, Yunus, Fakhar-Un-Nisa, Wu, Zhenghua, Li, Dawei
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2019
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844563/
https://ncbi.nlm.nih.gov/pubmed/31710263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336918.2019.1685928
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