Tributyltin chloride (TBT) induces RXRA down-regulation and lipid accumulation in human liver cells

A subset of environmental chemicals acts as “obesogens” as they increase adipose mass and lipid content in livers of treated rodents. One of the most studied class of obesogens are the tin-containing chemicals that have as a central moiety tributyltin (TBT), which bind and activate two nuclear hormo...

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Udgivet i:PLoS One
Main Authors: Stossi, Fabio, Dandekar, Radhika D., Johnson, Hannah, Lavere, Philip, Foulds, Charles E., Mancini, Maureen G., Mancini, Michael A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844554/
https://ncbi.nlm.nih.gov/pubmed/31710612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224405
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