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An integrated and semi-automated micro-scaled approach to profile cis-regulatory elements by histone modification ChIP-Seq for large-scale epigenetic studies.

Chromatin immunoprecipitation followed by sequencing (ChIP-Seq) is the preferred approach to map histone modifications and identify cis-regulatory DNA elements throughout the genome. Multiple methods have been described to increase the efficiency of library preparation and to reduce hands-on time as...

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Bibliographische Detailangaben
Veröffentlicht in:Methods Mol Biol
Hauptverfasser: Youhanna Jankeel, Diana, Cayford, Justin, Schmiedel, Benjamin Joachim, Vijayanand, Pandurangan, Seumois, Grégory
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844362/
https://ncbi.nlm.nih.gov/pubmed/29956160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7896-0_22
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