PD-L1 regulation by SDH5 via β-catenin/ZEB1 signaling

Programmed death-ligand 1 (PD-L1) is a crucial target for lung cancer immunotherapy. In lung cancer patients with high PD-L1 expression, blocking or reducing its expression can inhibit tumor growth. PD-L1 is regulated by signaling pathways, transcription factors and epigenetic factors, such as the G...

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Vydáno v:Oncoimmunology
Hlavní autoři: Tuo, Zhan, Zong, Yan, Li, Jie, Xiao, Guangqin, Zhang, Furong, Li, Guiling, Wang, Sihua, Lv, Yi, Xia, Jiahong, Liu, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844322/
https://ncbi.nlm.nih.gov/pubmed/31741753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1655361
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