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CDK12 Activity-Dependent Phosphorylation Events in Human Cells

We asked whether the C-terminal repeat domain (CTD) kinase, CDK12/CyclinK, phosphorylates substrates in addition to the CTD of RPB1, using our CDK12(analog-sensitive) HeLa cell line to investigate CDK12 activity-dependent phosphorylation events in human cells. Characterizing the phospho-proteome bef...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Bartkowiak, Bartlomiej, Yan, Christopher M., Soderblom, Erik J., Greenleaf, Arno L.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844070/
https://ncbi.nlm.nih.gov/pubmed/31652541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9100634
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