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Sustained Neurotrophin Release from Protein Nanoparticles Mediated by Matrix Metalloproteinases Induces the Alignment and Differentiation of Nerve Cells

The spatial and temporal availability of cytokines, and the microenvironments this creates, is critical to tissue development and homeostasis. Creating concentration gradients in vitro using soluble proteins is challenging as they do not provide a self-sustainable source. To mimic the sustained cyto...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Matsuzaki, Yuka, Maruta, Rina, Takaki, Keiko, Kotani, Eiji, Kato, Yasuko, Yoshimura, Ryoichi, Endo, Yasuhisa, Whitty, Ciara, Pernstich, Christian, Gandhi, Raj, Jones, Michael, Mori, Hajime
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6843502/
https://ncbi.nlm.nih.gov/pubmed/31546991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9100510
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