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The Link That Binds: The Linker of Hsp70 as a Helm of the Protein’s Function

The heat shock 70 (Hsp70) family of molecular chaperones plays a central role in maintaining cellular proteostasis. Structurally, Hsp70s are composed of an N-terminal nucleotide binding domain (NBD) which exhibits ATPase activity, and a C-terminal substrate binding domain (SBD). The binding of ATP a...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Chakafana, Graham, Zininga, Tawanda, Shonhai, Addmore
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6843406/
https://ncbi.nlm.nih.gov/pubmed/31569820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9100543
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