Physicochemical Characterization and Antioxidant Activity Evaluation of Idebenone/Hydroxypropyl-β-Cyclodextrin Inclusion Complex †

Idebenone (IDE) is an antioxidant drug active at the level of the central nervous system (CNS), whose poor water solubility limits its clinical application. An IDE/2-hydroxypropyl-β-cyclodextrin (IDE/HP-β-CD) inclusion complex was investigated by combining experimental methods and theoretical approa...

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Udgivet i:Biomolecules
Main Authors: Venuti, Valentina, Crupi, Vincenza, Fazio, Barbara, Majolino, Domenico, Acri, Giuseppe, Testagrossa, Barbara, Stancanelli, Rosanna, De Gaetano, Federica, Gagliardi, Agnese, Paolino, Donatella, Floresta, Giuseppe, Pistarà, Venerando, Rescifina, Antonio, Ventura, Cinzia A.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6843366/
https://ncbi.nlm.nih.gov/pubmed/31557949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9100531
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