HMGB1-triggered inflammation inhibition of notoginseng leaf triterpenes against cerebral ischemia and reperfusion injury via MAPK and NF-κB signaling pathways

Ischemic stroke is a clinically common cerebrovascular disease whose main risks include necrosis, apoptosis and cerebral infarction, all caused by cerebral ischemia and reperfusion (I/R) injury. This process has particular significance for the treatment of stroke patients. Notoginseng leaf triterpen...

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Bibliographische Detailangaben
Veröffentlicht in:Biomolecules
Hauptverfasser: Xie, Weijie, Zhu, Ting, Dong, Xi, Nan, Fengwei, Meng, Xiangbao, Zhou, Ping, Sun, Guibo, Sun, Xiaobo
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6843331/
https://ncbi.nlm.nih.gov/pubmed/31547018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9100512
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